The severity of mitochondrialRelated to the mitochondria. disease symptoms is different from person to person. The most common symptoms are:
- Poor growth and failure to thrive (in children)
- Loss of muscle coordination, muscle weakness and pain, low tone, exercise intolerance • Neurological problems, seizuresEpisodes of abnormal electrical activity in the brain.
- Autism, autistic spectrum, autism-like features
- Visual and/or hearing problems
- Developmental delays, learning disabilities
- Movement disorders
- Heart, liver or kidney disease
- GastrointestinalGI disorders, including severe constipation, diarrhea, swallowing difficulty, repeated vomiting, cramping, reflux
- Diabetes
- Increased risk of infection
- Neurological issues, including difficult to treat seizures, migraines, and stroke or stroke like events
- Thyroid and/or adrenal dysfunction
- Autonomic dysfunction (may affect the functioning of the heart, bladder, intestines, sweat glands, pupils, and blood vessels
- Respiratory issues
- Lactic acidosis (the buildup of lactate in the body, which results in an excessively low pH in the bloodstream)
- Neuropsychological changes characterized by confusion, disorientation, dementiaLoss of cognitive functioning — thinking, remembering, and reasoning — to the extent that it interferes with a person's daily life, and memory loss
