Expert Series: Ceramides: The Unmasked Drivers of VLCADD-Induced Heart Failure
Expert Series: Ceramides: The Unmasked Drivers of VLCADD-Induced Heart Failure
Despite advances in newborn screening and treatment of fatty acid oxidation disorders, patients with very-long-chain acyl-CoA dehydrogenase deficiency (VLCADD) continue to suffer from heart failure. Marie Norris will discuss her preliminary data which suggests that lipotoxicity, largely mediated by the accumulation of ceramides, is a major contributor to VLCADD-induced heart failure. Ms. Norris will discuss […]